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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1LB All Species: 43.64
Human Site: S452 Identified Species: 64
UniProt: Q86YB8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YB8 NP_063944.3 467 53543 S452 A F G R L S T S I R D L Q N F
Chimpanzee Pan troglodytes XP_001156276 467 53719 S452 A F G R L S T S I R D L Q N F
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 S453 A F G R I S T S V K E L E N F
Dog Lupus familis XP_546074 753 83528 S738 A F G R L S T S I R E L Q N F
Cat Felis silvestris
Mouse Mus musculus Q8R2E9 467 53500 S452 A F G R L S T S I R E L Q N F
Rat Rattus norvegicus Q8R4A1 464 54000 S449 A F G R I S T S V R E L E N F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512742 679 76557 S664 A F G R L S T S I R E L Q N F
Chicken Gallus gallus XP_419554 467 53247 S452 A F G R L S T S I K E L Q N F
Frog Xenopus laevis Q6DD71 465 53720 S451 A F G R I S T S V Q E L E N F
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 K444 R F R K N L H K C Q R V E E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 A464 E I V A L F N A F G R L S N S
Honey Bee Apis mellifera XP_623933 471 55049 S457 I N A F G R L S E S I F E L D
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 S444 S F G R Y S S S I L E V D N F
Sea Urchin Strong. purpuratus XP_796844 897 101920 E877 G S I V E I E E F Q E L L S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 A449 R L M E D Q I A K V S A K P A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 S477 T Y A R L S S S L D A I Q K F
Conservation
Percent
Protein Identity: 100 98.5 60 60.2 N.A. 94 59.3 N.A. 63.3 87.5 58.6 52.5 N.A. 46.1 49 40.7 25.8
Protein Similarity: 100 98.9 75 61.3 N.A. 96.5 74.5 N.A. 66.7 92.7 74.9 68 N.A. 63.9 65.8 59.2 35.9
P-Site Identity: 100 100 66.6 93.3 N.A. 93.3 73.3 N.A. 93.3 86.6 66.6 6.6 N.A. 20 6.6 53.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 33.3 N.A. 26.6 13.3 80 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.8 N.A. 28.5
Protein Similarity: N.A. N.A. N.A. 57.3 N.A. 39.6
P-Site Identity: N.A. N.A. N.A. 0 N.A. 40
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 57 0 13 7 0 0 0 13 0 0 7 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 0 7 13 0 7 0 7 % D
% Glu: 7 0 0 7 7 0 7 7 7 0 57 0 32 7 0 % E
% Phe: 0 69 0 7 0 7 0 0 13 0 0 7 0 0 69 % F
% Gly: 7 0 63 0 7 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 7 0 19 7 7 0 44 0 7 7 0 0 0 % I
% Lys: 0 0 0 7 0 0 0 7 7 13 0 0 7 7 0 % K
% Leu: 0 7 0 0 50 7 7 0 7 7 0 69 7 7 7 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 7 0 7 0 0 0 0 0 0 69 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 19 0 0 44 0 7 % Q
% Arg: 13 0 7 69 0 7 0 0 0 38 13 0 0 0 0 % R
% Ser: 7 7 0 0 0 69 13 75 0 7 7 0 7 7 7 % S
% Thr: 7 0 0 0 0 0 57 0 0 0 0 0 0 0 0 % T
% Val: 0 0 7 7 0 0 0 0 19 7 0 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _